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    Perimenopause supplements compared

    Every product we hold for this goal, side by side: what is in it, how you take it, what it costs a day, and who it is not for.

    The comparison.

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    These flags come from documented cautions for the ingredients involved. They are a prompt to check with a pharmacist or clinician, not a safety verdict on the product.

    Showing 50 of 50 products.

    Perimenopause supplements compared
    ProductKey activesFormDosePricePer dayBest forNot for
    ARTAH Essential CreatineARTAHCreatine monohydratePowderOne serving daily, 30-day pouch£28.0093pStrength training, Protecting muscle in midlifeAnyone not doing resistance training, who will see little from it
    ARTAH Essential D3/K2ARTAHVitamin D3, Vitamin K2 MK-7CapsuleOne capsule daily, 60-day jar£26.0043pUK winter, Low sun exposureAnyone taking very high unsupervised doses without a blood test
    ARTAH Essential MagnesiumARTAHMagnesium blendCapsuleDaily dose as directed on the label£24.00-Broken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    ARTAH Essential OmegasARTAHEPA, DHACapsuleDaily dose as directed, 30-day jar£32.00£1.07Period pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Bare Biology Beam & Balance Vitamin D3 with K2 SprayBare BiologyVitamin D3, Vitamin K2SprayDaily spray as directed£21.95-UK winter, Low sun exposureAnyone taking very high unsupervised doses without a blood test
    Bare Biology High Flyer Creatine MonohydrateBare BiologyCreatine monohydrate 5g per scoopPowderOne 5g scoop daily, any time of day£34.95-Strength training, Protecting muscle in midlifeAnyone not doing resistance training, who will see little from it
    Bare Biology Life & Soul Omega-3 Daily CapsulesBare BiologyEPA, DHA 1,700mg combinedSoftgelTwo capsules daily with food£32.95-Period pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Bare Biology Ready & Rested Magnesium BisglycinateBare BiologyMagnesium bisglycinate 375mgCapsuleThree capsules daily for the full 375mg£34.9958pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Bare Biology Skinful Pure Marine CollagenBare BiologyMarine collagen peptides 5gPowderOne scoop, around 5g, daily in a drink£39.95-Adding protein simply, Joint comfort alongside strength workAnyone already meeting protein needs and expecting a visible skin change
    Cycle ElixirARTAHMyo-inositol, Vitamin B6 (P5P), Magnesium, ChasteberryPowderOne scoop daily in water£48£1.60PCOS, PMDD, Irregular cyclesPregnancy, Anyone on hormonal contraception (check with clinician)
    Cycle Support PackPerelelVitamin B6, Magnesium glycinate, Calcium, ChasteberryCapsuleOne sachet daily, matched to cycle phase£42/month£1.50PMS and mild PMDD, Regular menstrual cycles, Wanting cycle-aware supportPregnancy, Post-menopause, Very irregular cycles
    Daily Multi Nutrient for WomenWild NutritionIron, Vitamin D3, Vitamin K2, B-complexCapsuleTwo capsules daily with food£30/month£2.00Daily foundational nutrition, Women in their reproductive years, Anyone starting from scratchPost-menopausal women (iron content), Anyone on prescribed iron already
    DR.VEGAN Creatine & BCAADR.VEGANCreatine monohydrate, BCAAsPowderOne serving daily, on training and rest days£32.99-Strength training, Protecting muscle in midlife, Hitting protein targets around trainingAnyone not doing resistance training, who will see little from it, Anyone already comfortably meeting protein needs from food
    DR.VEGAN Magnesium GlycinateDR.VEGANMagnesium bisglycinateCapsuleTwo capsules daily, ideally in the evening£19.9967pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    DR.VEGAN PMS HeroDR.VEGANChasteberry, Vitamin B6, Magnesium, AshwagandhaCapsuleTwo capsules daily through the cycle£26.9990pPremenstrual symptoms, as a time-limited trial, Broken sleep, Night-time crampsLong-term use at high dose without review, Anyone expecting it to treat hormonal symptoms directly, Anyone with a liver condition or taking thyroid medication
    DR.VEGAN Protein & Creatine SuperblendDR.VEGANPlant protein, Creatine monohydratePowderOne scoop daily, typically after training£36.99-Hitting protein targets around training, Strength training, Protecting muscle in midlifeAnyone already comfortably meeting protein needs from food, Anyone not doing resistance training, who will see little from it
    DR.VEGAN Vegan Omega 3DR.VEGANAlgal EPA, Algal DHACapsuleTwo capsules daily with food£29.99100pPeriod pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    DR.VEGAN Vitamin D3 & K2DR.VEGANVitamin D3, Vitamin K2 MK-7CapsuleOne capsule daily with a meal containing fat£12.9922pUK winter, Low sun exposureAnyone taking very high unsupervised doses without a blood test
    Igennus Advanced Hydrolysed Collagen PeptidesIgennus Healthcare NutritionBovine collagen peptidesPowderOne serving daily in a drink, 40 servings per pack£28.9572pAdding protein simply, Joint comfort alongside strength work, Hitting protein targets around trainingAnyone already meeting protein needs and expecting a visible skin change, Anyone already comfortably meeting protein needs from food
    Igennus Triple Magnesium ComplexIgennus Healthcare NutritionMagnesium citrate, bisglycinate, taurateTabletTwo tablets daily, split morning and evening£16.9556pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Igennus Vegan Omega-3 Algae OilIgennus Healthcare NutritionAlgal DHA 400mg, Algal EPA 200mgSoftgelTwo softgels daily, one morning and one evening£22.9577pPeriod pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Igennus Vegepa EPA with Evening Primrose OilIgennus Healthcare NutritionEPA, GLA from evening primrose oilSoftgelTwo softgels daily with food£15.9553pPeriod pain, Low oily fish intake, Cyclical breast tenderness, as a trialAnyone buying on capsule count rather than EPA and DHA content, Anyone expecting it to shift severe premenstrual mood symptoms
    Liposomal Magnesium BisglycinateElle SeraMagnesium bisglycinate (liposomal)LiquidTypically taken in the evening. Compare elemental magnesium per serving against the 300mg to 400mg range used in most studies.£40.00£1.33Trouble falling asleep or staying asleep, Muscle cramps, restless legs or night-time tension, Cycle-related tension and irritability, Anyone who has found other magnesium forms upsetting to the gutKidney impairment without medical advice, Anyone already taking magnesium in a multivitamin at a full dose, People wanting the cheapest effective option
    Liposomal Tripeptide CollagenElle SeraTripeptide collagen (liposomal)LiquidDaily, consistently. Judge after twelve weeks, not four. Check the peptide dose per serving against the 2.5g to 10g range used in trials.From £69.95 per month£2.33Skin hydration and elasticity through perimenopause and beyond, Anyone who prefers a convenient daily format over powder, People who will genuinely take it every day for three monthsVegetarians and vegans, as collagen is animal derived, Anyone with a fish or bovine allergy, depending on the source, Anyone looking for the best cost per gram of peptide
    Magnesium EaseThe Nue Co.Magnesium chloride (topical)SpraySix sprays on legs and stomach 30 minutes before bed£35£1.17Restless legs, Sleep-onset insomnia, Post-workout recoveryBroken skin, Anyone already on high-dose oral magnesium
    Magnesium Glycinate 400BetterYouMagnesium bisglycinate 400mgCapsuleTwo tablets one hour before bed£1860pSleep-onset insomnia, Muscle cramps, Perimenopausal sleep changesKidney disease, Anyone on high-dose diuretics
    Menopace OriginalVitabioticsB vitamins, Vitamin D, ZincTabletOne tablet daily with food.~£10-Filling nutrient gaps in perimenopause, Women who want a non-botanical optionAnyone expecting symptom relief on its own, Anyone who has not discussed HRT yet
    Peri-BoostMPowderSage, Maca, B-complex, Magnesium, Vitamin D3PowderOne scoop daily in smoothie or water£55/month£1.83Perimenopause, Hot flushes, Perimenopausal fatiguePregnancy, Hormone-sensitive cancers, On HRT (check with clinician)
    Perimenopause Multi-NutrientHealth & HerSage, Red clover, Vitamin B6CapsuleTwo capsules daily with food.~£24-Early perimenopause alongside lifestyle change, Women not yet on HRTHormone-sensitive cancer history, Anyone on tamoxifen or anticoagulants, Pregnancy or breastfeeding
    Pregnacare MaxVitabioticsFolic acid 400ug, Vitamin D 10ug, DHA omega-3Tablets + capsulesTwo tablets plus one omega-3 capsule daily with food.~£30-Trying to conceive or already pregnant, Anyone who wants folic acid, vitamin D and DHA in one packAnyone taking a separate vitamin A supplement, Anyone already on a prescribed pregnancy multivitamin
    The Collagen ElixirWelleCoMarine collagenPowderOne scoop daily in water£49£1.63Skin elasticity and hydration, Perimenopausal skin changes, Anyone already eating enough proteinFish allergy, Vegans and vegetarians, Anyone wanting a high-dose collagen
    The Goddess ElixirWelleCo--Two capsules daily with food£49-Hot flushes and night sweats, Perimenopause alongside lifestyle change, Women who prefer a botanical first stepAnyone with a hormone-sensitive cancer history without GP advice, Pregnancy or breastfeeding, Anyone on tamoxifen or anticoagulants
    The Golden PillElle Sera--One capsule daily, taken consistently. Most botanical effects, where present, take six to twelve weeks to show.From £69.95 per month-Perimenopausal symptom support alongside clinical care, Women who want a single daily capsule rather than a stack, Anyone starting out and unsure where to beginPregnancy or breastfeeding, Hormone-sensitive cancers without specialist advice, Anyone on prescribed HRT or SSRIs without checking interactions, Replacing a hormone review or GP appointment
    The Perimenopause PackWelleCo--Greens powder each morning, two Goddess capsules daily£79-Starting perimenopause support from scratch, Anyone who skips mealsAnyone already on a comprehensive multivitamin, Hormone-sensitive history without GP advice
    Together Health Algae Omega 3Together HealthAlgal DHA, Algal EPASoftgelOne softgel per day£17.9560pPeriod pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Together Health Marine MagnesiumTogether HealthMarine-sourced magnesiumCapsuleOne capsule per day£8.9530pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Together Health Vitamin D3 and K2Together HealthVitamin D3, Vitamin K2CapsuleOne capsule per day£15.9553pUK winter, Low sun exposureAnyone taking very high unsupervised doses without a blood test
    Viridian High Potency Magnesium BisglycinateViridian NutritionMagnesium bisglycinateCapsuleTwo capsules daily for the full dose£16.0554pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Viridian Organic Sage 400mgViridian NutritionOrganic sage 400mgCapsuleOne capsule daily£9.4532pMild night sweats, as a short trialAnyone with disruptive flushes who has not discussed HRT
    Viridian Red Clover ExtractViridian NutritionRed clover isoflavonesCapsuleOne capsule daily with food£16.9528pMild flushes when HRT is not an optionAnyone with disruptive flushes who has not discussed HRT
    Viridian Vitamin D3 & K2Viridian NutritionVitamin D3, Vitamin K2CapsuleOne capsule daily£31.8535pUK winter, Low sun exposureAnyone taking very high unsupervised doses without a blood test
    Wellwoman MaxVitabioticsOmega-3 EPA/DHA, Iron, B vitaminsTablets + capsulesOne tablet plus one omega-3 capsule daily with food.~£20-Women who do not eat oily fish, Anyone consolidating several supplementsAnyone already taking a good omega-3, Pregnancy, use Pregnacare instead
    Wild Nutrition Collagen 500 PlusWild NutritionCollagen peptides, Vitamin CCapsuleDaily dose as directed£42.50£1.42Adding protein simply, Joint comfort alongside strength work, Taking alongside ironAnyone already meeting protein needs and expecting a visible skin change, Anyone taking gram doses expecting to prevent colds
    Wild Nutrition Endo SupportWild NutritionMagnesium, B vitamins, Botanical blendCapsuleDaily dose as directed£46.50£1.55Nutritional support alongside specialist careAnyone expecting it to treat hormonal symptoms directly, Anyone buying on capsule count rather than EPA and DHA content, Long-term use at high dose without review
    Wild Nutrition Food-Grown MagnesiumWild NutritionMagnesium (food-grown)CapsuleOne capsule daily with food, 30 days per jar£24.0080pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Wild Nutrition Food-Grown Vitamin DWild NutritionVitamin DCapsuleOne capsule daily with food£21.0070pUK winter, Low sun exposureAnyone taking very high unsupervised doses without a blood test
    Wild Nutrition Menopause ComplexWild NutritionMagnesium, Vitamin D, B vitamins, BotanicalsCapsuleDaily dose as directed£42.00£1.40Broken sleep, Night-time cramps, UK winterAnyone expecting it to treat hormonal symptoms directly, Anyone taking very high unsupervised doses without a blood test, Long-term use at high dose without review
    Wild Nutrition Premenstrual SupportWild NutritionMagnesium, Vitamin B6, Botanical blendCapsuleDaily dose as directed£41.00£1.37Broken sleep, Night-time cramps, Premenstrual symptoms, as a time-limited trialAnyone expecting it to treat hormonal symptoms directly, Long-term use at high dose without review
    Wild Nutrition Pure Strength Omega 3Wild NutritionEPA, DHASoftgelDaily dose as directed, 30 days per jar£44.00£1.47Period pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Wild Nutrition Women's Daily Multi NutrientWild NutritionMultivitamin, Iron, Vitamin DCapsuleDaily dose as directed with food£44.00£1.47UK winter, Low sun exposure, Confirmed low ferritinAnyone taking very high unsupervised doses without a blood test, Anyone who has not had ferritin checked, Long-term use at high dose without review, Anyone taking gram doses expecting to prevent colds

    Prices are the brand's UK list price at the time of writing and change often. Cost per day is calculated from pack size and the label's daily serving, and is shown only where the brand publishes both. We do not accept payment for inclusion or placement.

    When a supplement is not the answer

    If hot flushes are waking you nightly, if your mood has changed in a way that frightens you, if bleeding has become heavy or unpredictable, or if sex has become painful, those are clinical problems with clinical answers. HRT, vaginal oestrogen and non-hormonal prescribed options all have far better evidence than anything on this page. A supplement taken instead of that conversation costs you time you do not need to lose.

    Speak to a menopause clinician

    Questions people ask.

    Which perimenopause supplements should I buy?
    No supplement treats perimenopause. The options with the most support are magnesium for sleep and cramps, vitamin D for bone health, and protein plus creatine alongside resistance training to protect muscle. Black cohosh has mixed evidence for hot flushes. For disruptive symptoms, HRT is the treatment with the strongest evidence.
    How is cost per day calculated?
    We divide the brand's UK list price by the number of days a pack lasts, using the pack size and the daily serving printed on the label. Where a brand does not publish both numbers we leave the figure blank rather than estimate it.
    Are these products ranked or paid placements?
    No. The table is ordered alphabetically and nobody pays to appear in it. We do not hold ratings, accreditations or trial results for individual products, so we do not publish any.
    Can I take more than one of these together?
    Often yes, but check the total dose of any nutrient that appears in more than one product, and check interactions with your medication with a pharmacist first. Iron in particular should only be taken when a blood test shows you need it.
    What is the best supplement for perimenopause?
    There is no single best one. Magnesium has the most support for sleep and cramps, vitamin D matters for bone health in the UK, and protein plus creatine alongside strength training protects the muscle you lose fastest in this decade.
    Do perimenopause supplements actually work?
    Some help specific symptoms. None treat the hormonal transition itself. Products claiming to balance hormones or replace HRT are overstating what a supplement can do.
    Should I take supplements or HRT?
    They answer different questions. HRT treats the oestrogen decline and has the strongest evidence for flushes, sleep, mood and bone protection. Supplements address nutrient gaps and general resilience. Many women reasonably do both.
    Read the full perimenopause supplements guide

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    Food supplements are not medicines and are not intended to diagnose, treat or cure any condition. They should not replace a varied diet or prescribed treatment. If you are pregnant, breastfeeding, taking medication or managing a diagnosed condition, check with a pharmacist or clinician before starting anything on this page. We do not accept payment for inclusion or placement. Where a link earns us a commission we say so on the product page. Last reviewed 27 August 2026.