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    PMDD supplements compared

    Every product we hold for this goal, side by side: what is in it, how you take it, what it costs a day, and who it is not for.

    The comparison.

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    These flags come from documented cautions for the ingredients involved. They are a prompt to check with a pharmacist or clinician, not a safety verdict on the product.

    Showing 32 of 32 products.

    PMDD supplements compared
    ProductKey activesFormDosePricePer dayBest forNot for
    ARTAH Essential MagnesiumARTAHMagnesium blendCapsuleDaily dose as directed on the label£24.00-Broken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    ARTAH Essential OmegasARTAHEPA, DHACapsuleDaily dose as directed, 30-day jar£32.00£1.07Period pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Bare Biology Life & Soul Omega-3 Daily CapsulesBare BiologyEPA, DHA 1,700mg combinedSoftgelTwo capsules daily with food£32.95-Period pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Bare Biology Ready & Rested Magnesium BisglycinateBare BiologyMagnesium bisglycinate 375mgCapsuleThree capsules daily for the full 375mg£34.9958pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Cycle ElixirARTAHMyo-inositol, Vitamin B6 (P5P), Magnesium, ChasteberryPowderOne scoop daily in water£48£1.60PCOS, PMDD, Irregular cyclesPregnancy, Anyone on hormonal contraception (check with clinician)
    Cycle Support PackPerelelVitamin B6, Magnesium glycinate, Calcium, ChasteberryCapsuleOne sachet daily, matched to cycle phase£42/month£1.50PMS and mild PMDD, Regular menstrual cycles, Wanting cycle-aware supportPregnancy, Post-menopause, Very irregular cycles
    Daily Multi Nutrient for WomenWild NutritionIron, Vitamin D3, Vitamin K2, B-complexCapsuleTwo capsules daily with food£30/month£2.00Daily foundational nutrition, Women in their reproductive years, Anyone starting from scratchPost-menopausal women (iron content), Anyone on prescribed iron already
    DR.VEGAN Magnesium GlycinateDR.VEGANMagnesium bisglycinateCapsuleTwo capsules daily, ideally in the evening£19.9967pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    DR.VEGAN PMS HeroDR.VEGANChasteberry, Vitamin B6, Magnesium, AshwagandhaCapsuleTwo capsules daily through the cycle£26.9990pPremenstrual symptoms, as a time-limited trial, Broken sleep, Night-time crampsLong-term use at high dose without review, Anyone expecting it to treat hormonal symptoms directly, Anyone with a liver condition or taking thyroid medication
    DR.VEGAN Vegan Omega 3DR.VEGANAlgal EPA, Algal DHACapsuleTwo capsules daily with food£29.99100pPeriod pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Igennus Triple Magnesium ComplexIgennus Healthcare NutritionMagnesium citrate, bisglycinate, taurateTabletTwo tablets daily, split morning and evening£16.9556pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Igennus Vegan Omega-3 Algae OilIgennus Healthcare NutritionAlgal DHA 400mg, Algal EPA 200mgSoftgelTwo softgels daily, one morning and one evening£22.9577pPeriod pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Igennus Vegepa EPA with Evening Primrose OilIgennus Healthcare NutritionEPA, GLA from evening primrose oilSoftgelTwo softgels daily with food£15.9553pPeriod pain, Low oily fish intake, Cyclical breast tenderness, as a trialAnyone buying on capsule count rather than EPA and DHA content, Anyone expecting it to shift severe premenstrual mood symptoms
    Liposomal Magnesium BisglycinateElle SeraMagnesium bisglycinate (liposomal)LiquidTypically taken in the evening. Compare elemental magnesium per serving against the 300mg to 400mg range used in most studies.£40.00£1.33Trouble falling asleep or staying asleep, Muscle cramps, restless legs or night-time tension, Cycle-related tension and irritability, Anyone who has found other magnesium forms upsetting to the gutKidney impairment without medical advice, Anyone already taking magnesium in a multivitamin at a full dose, People wanting the cheapest effective option
    Magnesium EaseThe Nue Co.Magnesium chloride (topical)SpraySix sprays on legs and stomach 30 minutes before bed£35£1.17Restless legs, Sleep-onset insomnia, Post-workout recoveryBroken skin, Anyone already on high-dose oral magnesium
    Magnesium Glycinate 400BetterYouMagnesium bisglycinate 400mgCapsuleTwo tablets one hour before bed£1860pSleep-onset insomnia, Muscle cramps, Perimenopausal sleep changesKidney disease, Anyone on high-dose diuretics
    Menopace OriginalVitabioticsB vitamins, Vitamin D, ZincTabletOne tablet daily with food.~£10-Filling nutrient gaps in perimenopause, Women who want a non-botanical optionAnyone expecting symptom relief on its own, Anyone who has not discussed HRT yet
    Peri-BoostMPowderSage, Maca, B-complex, Magnesium, Vitamin D3PowderOne scoop daily in smoothie or water£55/month£1.83Perimenopause, Hot flushes, Perimenopausal fatiguePregnancy, Hormone-sensitive cancers, On HRT (check with clinician)
    Perimenopause Multi-NutrientHealth & HerSage, Red clover, Vitamin B6CapsuleTwo capsules daily with food.~£24-Early perimenopause alongside lifestyle change, Women not yet on HRTHormone-sensitive cancer history, Anyone on tamoxifen or anticoagulants, Pregnancy or breastfeeding
    Pregnacare MaxVitabioticsFolic acid 400ug, Vitamin D 10ug, DHA omega-3Tablets + capsulesTwo tablets plus one omega-3 capsule daily with food.~£30-Trying to conceive or already pregnant, Anyone who wants folic acid, vitamin D and DHA in one packAnyone taking a separate vitamin A supplement, Anyone already on a prescribed pregnancy multivitamin
    Together Health Algae Omega 3Together HealthAlgal DHA, Algal EPASoftgelOne softgel per day£17.9560pPeriod pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Together Health Marine MagnesiumTogether HealthMarine-sourced magnesiumCapsuleOne capsule per day£8.9530pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Viridian High Potency Magnesium BisglycinateViridian NutritionMagnesium bisglycinateCapsuleTwo capsules daily for the full dose£16.0554pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Viridian Organic Evening Primrose OilViridian NutritionGLA from evening primrose oilLiquidOne serving daily, 40 servings per bottle£23.0558pCyclical breast tenderness, as a trialAnyone expecting it to shift severe premenstrual mood symptoms
    Wellwoman MaxVitabioticsOmega-3 EPA/DHA, Iron, B vitaminsTablets + capsulesOne tablet plus one omega-3 capsule daily with food.~£20-Women who do not eat oily fish, Anyone consolidating several supplementsAnyone already taking a good omega-3, Pregnancy, use Pregnacare instead
    Wellwoman OriginalVitabioticsIron, B vitamins, Evening primrose oilCapsuleOne capsule daily with food.~£12-Busy weeks and irregular eating, A general nutritional floorAnyone with a diagnosed deficiency needing treatment doses, Pregnancy, use a pregnancy formula instead
    Wild Nutrition Endo SupportWild NutritionMagnesium, B vitamins, Botanical blendCapsuleDaily dose as directed£46.50£1.55Nutritional support alongside specialist careAnyone expecting it to treat hormonal symptoms directly, Anyone buying on capsule count rather than EPA and DHA content, Long-term use at high dose without review
    Wild Nutrition Food-Grown MagnesiumWild NutritionMagnesium (food-grown)CapsuleOne capsule daily with food, 30 days per jar£24.0080pBroken sleep, Night-time crampsAnyone expecting it to treat hormonal symptoms directly
    Wild Nutrition Menopause ComplexWild NutritionMagnesium, Vitamin D, B vitamins, BotanicalsCapsuleDaily dose as directed£42.00£1.40Broken sleep, Night-time cramps, UK winterAnyone expecting it to treat hormonal symptoms directly, Anyone taking very high unsupervised doses without a blood test, Long-term use at high dose without review
    Wild Nutrition Premenstrual SupportWild NutritionMagnesium, Vitamin B6, Botanical blendCapsuleDaily dose as directed£41.00£1.37Broken sleep, Night-time cramps, Premenstrual symptoms, as a time-limited trialAnyone expecting it to treat hormonal symptoms directly, Long-term use at high dose without review
    Wild Nutrition Pure Strength Omega 3Wild NutritionEPA, DHASoftgelDaily dose as directed, 30 days per jar£44.00£1.47Period pain, Low oily fish intakeAnyone buying on capsule count rather than EPA and DHA content
    Wild Nutrition Women's Daily Multi NutrientWild NutritionMultivitamin, Iron, Vitamin DCapsuleDaily dose as directed with food£44.00£1.47UK winter, Low sun exposure, Confirmed low ferritinAnyone taking very high unsupervised doses without a blood test, Anyone who has not had ferritin checked, Long-term use at high dose without review, Anyone taking gram doses expecting to prevent colds

    Prices are the brand's UK list price at the time of writing and change often. Cost per day is calculated from pack size and the label's daily serving, and is shown only where the brand publishes both. We do not accept payment for inclusion or placement.

    When a supplement is not the answer

    If your premenstrual weeks involve rage, despair, or thoughts of harming yourself, that is PMDD territory and it deserves treatment, not a capsule. Cycle tracking over two to three months plus a proper assessment is the route in. SSRIs used continuously or in the luteal phase, some hormonal approaches and structured psychological support all have real evidence behind them. If you are in crisis now, contact 999, Samaritans on 116 123, or your GP urgently.

    Read our PMDD guide

    Questions people ask.

    Which pmdd supplements should I buy?
    No supplement treats PMDD. Small trials suggest calcium at around 1,000-1,200mg daily, magnesium, vitamin B6 at 50-100mg and omega-3 may reduce some premenstrual symptoms. PMDD itself responds to SSRIs, certain hormonal approaches and structured support, so supplements should sit alongside clinical care, not instead of it.
    How is cost per day calculated?
    We divide the brand's UK list price by the number of days a pack lasts, using the pack size and the daily serving printed on the label. Where a brand does not publish both numbers we leave the figure blank rather than estimate it.
    Are these products ranked or paid placements?
    No. The table is ordered alphabetically and nobody pays to appear in it. We do not hold ratings, accreditations or trial results for individual products, so we do not publish any.
    Can I take more than one of these together?
    Often yes, but check the total dose of any nutrient that appears in more than one product, and check interactions with your medication with a pharmacist first. Iron in particular should only be taken when a blood test shows you need it.
    What supplements help PMDD?
    Calcium has the most PMS trial support, with smaller studies behind magnesium, vitamin B6 at 50-100mg and omega-3. None of these treat PMDD itself.
    Can supplements replace SSRIs for PMDD?
    No. SSRIs have far stronger evidence in PMDD, including when taken only in the luteal phase. Supplements are support alongside treatment.
    Should I take supplements all month or only before my period?
    Several, including B6 and magnesium, can be taken through the luteal phase only. Calcium is usually taken daily. Discuss the pattern with a clinician if you are tracking symptoms.
    Read the full pmdd supplements guide

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    Food supplements are not medicines and are not intended to diagnose, treat or cure any condition. They should not replace a varied diet or prescribed treatment. If you are pregnant, breastfeeding, taking medication or managing a diagnosed condition, check with a pharmacist or clinician before starting anything on this page. We do not accept payment for inclusion or placement. Where a link earns us a commission we say so on the product page. Last reviewed 27 August 2026.